Healthcare provider in white coat consulting with elderly male patient in modern medical office

Patient Selection

Cingal may be considered as part of the non-surgical management of knee osteoarthritis (OA) in appropriately selected patients. As with any intra-articular therapy, patient selection is based on clinical judgement, symptom profile, prior treatment history, and individual treatment goals.

Patient Profiles Commonly Considered

Cingal may be considered in adult patients who:

Have a clinical diagnosis of osteoarthritis of the knee
Present with symptomatic mild to moderate disease
Experience knee pain, stiffness, or functional limitation affecting daily activities
Have had an insufficient response to conservative measures, such as:
- Activity modification
- Exercise or physiotherapy
- Weight management
- Oral analgesics or NSAIDs (where appropriate)

Clinician holding a knee joint model while explaining treatment options to an older woman across a desk

Cingal may be particularly relevant for patients seeking a single injection intra-articular treatment option within a broader OA management strategy.

Positioning Within the Osteoarthritis Pain Management Pathway

Cingal is typically considered within a structured, non-surgical treatment approach to knee OA. It may be discussed when:

Symptoms persist despite initial conservative interventions
The patient is not ready for surgical intervention, or surgery is not yet indicated
There is a clinical preference to combine short-term anti-inflammatory effect with longer-term viscoelastic support in a single treatment episode

Cingal is not intended to replace foundational OA management strategies, such as movement-based therapy, but may be used in conjunction with rehabilitation programmes where clinically appropriate.

Healthcare professional examining patient's leg during physical therapy or medical consultation session.

Clinical Considerations

When assessing suitability, clinicians may take into account:

Symptom severity and pattern (pain, stiffness, mechanical symptoms)
Functional impact and activity goals
Previous intra-articular treatments and response
Comorbidities and concomitant medications
Patient expectations and willingness to engage in adjunctive care

Appropriate patient counselling regarding expected outcomes, variability of response, and role within an overall treatment plan is recommended.

Contraindications and Precautions

Cingal should be used in accordance with the approved Instructions for Use (IFU). Clinicians should review contraindications, warnings, and precautions prior to administration and ensure that patients meet eligibility criteria outlined in the IFU.

Shared Decision Making

As with all OA interventions, use of Cingal should form part of a shared decision-making process, balancing clinical findings with patient preferences and goals. Selection should be individualised rather than protocol-driven.

Please refer to the current Instructions for Use for full product indications, contraindications, and administration guidance at anikaifu.com(opens in a new tab).